【產品名稱】 Influenza A H1N1 ( A/California/04/2009 ) Neuraminidase 蛋白質
【產品規格】200ug、500ug、1mg
【產品Datasheet】11058-V07H (200ug)
Synonym:
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NA
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Protein Construction:
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A DNA sequence encoding the mature form of Influenza A virus ( A/California/04/2009 (H1N1) ) Neuraminidase ( ACP41107.1 )( His 36 - Lys 469 )was fused with a polyhistidine tag at the N-terminus
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Source:
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Influenza A H1N1
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Expression Host:
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Human Cells
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【產品特點】
H1N1 NA Protein QC Testing
Purity:
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> 73 % as determined by SDS-PAGE
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SDS-PAGE:
H1N1 NA protein
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Bio-activity:
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Inactive
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For active Neuraminidase (NA), please see H1N1 NA.
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Endotoxin:
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< 1.0 EU per μg of the protein as determined by the LAL method.
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Stability:
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Samples are stable for up to twelve months from date of receipt at -70℃
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Predicted N terminal:
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His
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Molecular Mass:
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The recombinant influenza H1N1 virus neuraminidase ( A/California/04/2009 (H1N1) ) comprises 450 amino acids with the predicted molecular mass of 50 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 65-75 kDa in SDS-PAGE under reducing conditions
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Formulation:
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Lyophilized from sterile PBS, pH 7.4
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【產品保存方法】
H1N1 NA Protein Usage Guide
Storage:
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Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Reconstitution:
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A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
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【其它相關產品】
H1N1 NA Protein Related Products & Topics
Related Areas:
【其它NA蛋白質產品】
Products
|
Source (CLICK for detailed Info. and Price)
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Molecule
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Description
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Cat. No
|
Protein
|
NA
|
Fc Tag
|
11058-V01H
| |
Protein
|
NA
|
His Tag
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11058-V07H
| |
Protein
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NA
|
His Tag
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11058-V07B
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Protein
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NA
|
His Tag
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11058-V07HC
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Protein
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NA
|
-
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11058-VNAHC
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Protein
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NA
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-
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11058-VNAHC1
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【H1N1流感NA抗體】
Antibodies:
Products
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Antigen Source
(CLICK for detailed Info. and Price) |
Antigen
Molecule |
Application
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Cat No
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MAb
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NA
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WB, ELISA
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11058-MM04
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【相關流感研究試劑】
Related Influenza Virus Research Tools
【H1N1蛋白質介紹】H1N1 NA Protein Description
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. NA, also called sialidases, specifically catalyze the hydrolysis removal of terminal sialic acid residues from viral and cellular glycoconjugates. It is known that HA binds to the sialic acid-containing receptors on the surface of host cells during initial infection, and at the end of an infectious cycle, NA cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. NA is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell. NA is a single-pass type I I membrane protein which exists as a homotetramer, and the transmembrane domain is involved in lipid raft association during intracellular transport. NA is suggested to play a role in the determination of host range restriction on replication and virulence. Nine subtypes of NA have been identified, and subtypes N1 and N2 have been positively linked to epidemics in man.
【文獻參考】References
1. Barman, S. et al., 2000, J. Virol. 74: 6538-6545.
2. Colman, PM. et al., 1983, Nature. 303: 41-44.
3. Suzuki, T. et al., 2005, J. Virol. 79: 11705-11715.
4. von, Itzstein, M. 2007, Nat. Rev. Drug. Discov. 6: 967-974.
【產品訂購資訊】
【供應廠商】萊恩生物科技有限公司
【公司電話】04-2523-9639
【業務專員】陳俊豪 0937-229803
【電子信箱】biolion0819@gmail.com
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