*** --老鼠Galectin-1(Gal1)重組蛋白, 50100-MNAE****
Mouse Galectin-1 / 14 kDa laminin-binding protein Protein
Mouse Lgals1 / Galectin-1 Protein Price Inquiry ( Available Sizes )
50100-MNAE
訂貨資料50100-MNAE
· ≥1mg Bulk:
Lgals1 / Galectin-1 Protein Product Information
Synonym :
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AA410090, Gal-1, Galbp, L-14.5, L14, Lect14, galectin-1
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Protein Construction:
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A DNA sequence encoding the mouse Lgals1 ( P16045 ) ( Met 1 - Glu 135 ) was expressed and purified
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Source:
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Mouse
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Expression Host:
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E.coli
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產品資料------
Lgals1 / Galectin-1 Protein QC Testing
Purity:
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> 95 % as determined by SDS-PAGE
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SDS-PAGE:
SDS-PAGE: 
Lgals1 protein
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Bio-activity:
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Measured by its ability to agglutinate human red blood cells.
The ED50 for this effect is typically 1-5 μg/ml. | |
Endotoxin:
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Please contact us for more information.
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Stability:
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Samples are stable for up to twelve months from date of receipt at -70℃
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Predicted N terminal:
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Met 1
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Molecular Mass:
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The recombinant mouse Lgals1 consists of 135 amino acids and migrates as an approximately 15 kDa band as predicted in SDS-PAGE under reducing conditions
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Formulation:
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Lyophilized from sterile PBS, 100 mM β-Lactose, pH 7.4
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Lgals1 / Galectin-1 Protein Usage Guide
Storage:
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Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Reconstitution:
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A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
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Lgals1 / Galectin-1 Protein Related Products & Topics
Related Areas:
更多Galectin 重組蛋白資料
Proteins:
Molecule
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Species
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Description //For Detailed Info. and Price------CLICK!
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Cat. No
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Galectin-1/GAL1/LGALS1
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Human
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10290-HNAE
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Galectin-1/GAL1/LGALS1
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Human
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10290-HNAE-E
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Galectin-1/GAL1/LGALS1
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Mouse
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50100-MNAE
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Galectin-1/GAL1/LGALS1
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Rat
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80248-RNAE
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Antibodies:
Molecule
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Species
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Description //For Detailed Info. and Price------CLICK!
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Cat. No
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Galectin-1/GAL1/LGALS1
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Human
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10290-RP02
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Lgals1 / Galectin-1 Protein Description
Mouse Galectin-1, also known as 14 kDa laminin-binding protein, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1 and LGALS1, is a secreted protein which contains one galectin domain. Galectins are a family of structurally related carbohydrate-binding proteins, which are defined by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and sequence similarities in the carbohydrate recognition domain. Galectin-1 / LGALS1 is expressed in placenta, maternal decidua and fetal membranes. Within placenta, it is expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, Galectin-1 / LGALS1 is expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Galectin-1 / LGALS1 is also expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. Galectin-1 / LGALS1 may regulate apoptosis, cell proliferation and cell differentiation. It binds beta-galactoside and a wide array of complex carbohydrates. Galectin-1 / LGALS1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Galectin-1 / LGALS1 has demonstrated a diverse range of activities in relation to cell survival and proliferation. In different circumstances, it acts as a mitogen, as an inhibitor of cell proliferation, and as a promoter of cellular apoptosis.
References
1. Demydenko,D. et al., 2009, Exp Oncol. 31 (2):74-9.
2. McGraw,J. et al., 2004, Eur J Neurosci. 20 (11):2872-80.
3. Di Lella S., et al., 2009, Biochemistry 48:786-791.
4. Rabinovich,G.A. 2005,Br J Cancer. 92 (7):1188-92.
5. Scott,K. et al., 2004, Glycoconj J. 19 (7-9):467-77.
【供應廠商】萊恩生物科技有限公司
【公司電話】04-2523-9639
【業務專員】陳俊豪 0937-229803
【電子信箱】biolion0819@gmail.com
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